| agost del 202517 d’ag. |  Ligue 1 | Metz 0–1 StrasbourgRegular Season - 1 | V |
| 24 d’ag. | Ligue 1 | Strasbourg1–0 NantesRegular Season - 2 | V |
| 31 d’ag. | Ligue 1 | Monaco 3–2StrasbourgRegular Season - 3 | D |
| setembre del 202514 de set. | Ligue 1 | Strasbourg1–0 Le HavreRegular Season - 4 | V |
| 21 de set. | Ligue 1 | Paris FC 2–3StrasbourgRegular Season - 5 | V |
| 26 de set. | Ligue 1 | Strasbourg1–2 MarseilleRegular Season - 6 | D |
| octubre del 202505 d’oct. | Ligue 1 | Strasbourg5–0 AngersRegular Season - 7 | V |
| 17 d’oct. | Ligue 1 | Paris Saint Germain 3–3StrasbourgRegular Season - 8 | E |
| 26 d’oct. | Ligue 1 | Lyon 2–1StrasbourgRegular Season - 9 | D |
| 29 d’oct. | Ligue 1 | Strasbourg3–0 AuxerreRegular Season - 10 | V |
| novembre del 202502 de nov. | Ligue 1 | Rennes 4–1StrasbourgRegular Season - 11 | D |
| 09 de nov. | Ligue 1 | Strasbourg2–0 LilleRegular Season - 12 | V |
| 22 de nov. | Ligue 1 | Lens 1–0StrasbourgRegular Season - 13 | D |
| 30 de nov. | Ligue 1 | Strasbourg1–2 Stade Brestois 29Regular Season - 14 | D |
| desembre del 202506 de des. | Ligue 1 | Toulouse 1–0StrasbourgRegular Season - 15 | D |
| 14 de des. | Ligue 1 | Strasbourg0–0 LorientRegular Season - 16 | E |
| gener del 202603 de gen. | Ligue 1 | Nice 1–1StrasbourgRegular Season - 17 | E |
| 18 de gen. | Ligue 1 | Strasbourg2–1MetzRegular Season - 18 | V |
| 25 de gen. | Ligue 1 | Lille1–4StrasbourgRegular Season - 19 | V |
| febrer del 202601 de febr. | Ligue 1 | Strasbourg1–2Paris Saint GermainRegular Season - 20 | D |
| 08 de febr. | Ligue 1 | Le Havre2–1StrasbourgRegular Season - 21 | D |
| 14 de febr. | Ligue 1 | Marseille2–2StrasbourgRegular Season - 22 | E |
| 22 de febr. | Ligue 1 | Strasbourg3–1LyonRegular Season - 23 | V |
| 27 de febr. | Ligue 1 | Strasbourg1–1LensRegular Season - 24 | E |
| març del 202607 de març | Ligue 1 | Auxerre0–0StrasbourgRegular Season - 25 | E |
| 15 de març | Ligue 1 | Strasbourg0–0Paris FCRegular Season - 26 | E |
| 22 de març | Ligue 1 | Nantes2–3StrasbourgRegular Season - 27 | V |
| abril del 202604 d’abr. | Ligue 1 | Strasbourg3–1NiceRegular Season - 28 | V |
| 19 d’abr. | Ligue 1 | Strasbourg0–3RennesRegular Season - 30 | D |
| 26 d’abr. | Ligue 1 | Lorient2–3StrasbourgRegular Season - 31 | V |
| maig del 202603 de maig | Ligue 1 | Strasbourg1–2ToulouseRegular Season - 32 | D |
| 10 de maig | Ligue 1 | Angers1–1StrasbourgRegular Season - 33 | E |
| 13 de maig | Ligue 1 | Stade Brestois 291–2StrasbourgRegular Season - 29 | V |
| 17 de maig | Ligue 1 | Strasbourg5–4MonacoRegular Season - 34 | V |
