| agost del 202516 d’ag. |  Premier League | Brighton 1–1 FulhamRegular Season - 1 | E |
| 24 d’ag. | Premier League | Everton 2–0BrightonRegular Season - 2 | D |
| 31 d’ag. | Premier League | Brighton2–1 Manchester CityRegular Season - 3 | V |
| setembre del 202513 de set. | Premier League | Bournemouth 2–1BrightonRegular Season - 4 | D |
| 20 de set. | Premier League | Brighton2–2 TottenhamRegular Season - 5 | E |
| 27 de set. | Premier League | Chelsea 1–3BrightonRegular Season - 6 | V |
| octubre del 202505 d’oct. | Premier League | Wolves 1–1BrightonRegular Season - 7 | E |
| 18 d’oct. | Premier League | Brighton2–1 NewcastleRegular Season - 8 | V |
| 25 d’oct. | Premier League | Manchester United 4–2BrightonRegular Season - 9 | D |
| novembre del 202501 de nov. | Premier League | Brighton3–0 LeedsRegular Season - 10 | V |
| 09 de nov. | Premier League | Crystal Palace 0–0BrightonRegular Season - 11 | E |
| 22 de nov. | Premier League | Brighton2–1 BrentfordRegular Season - 12 | V |
| 30 de nov. | Premier League | Nottingham Forest 0–2BrightonRegular Season - 13 | V |
| desembre del 202503 de des. | Premier League | Brighton3–4 Aston VillaRegular Season - 14 | D |
| 07 de des. | Premier League | Brighton1–1 West HamRegular Season - 15 | E |
| 13 de des. | Premier League | Liverpool 2–0BrightonRegular Season - 16 | D |
| 20 de des. | Premier League | Brighton0–0 SunderlandRegular Season - 17 | E |
| 27 de des. | Premier League | Arsenal 2–1BrightonRegular Season - 18 | D |
| 30 de des. | Premier League | West Ham2–2BrightonRegular Season - 19 | E |
| gener del 202603 de gen. | Premier League | Brighton2–0 BurnleyRegular Season - 20 | V |
| 07 de gen. | Premier League | Manchester City1–1BrightonRegular Season - 21 | E |
| 19 de gen. | Premier League | Brighton1–1BournemouthRegular Season - 22 | E |
| 24 de gen. | Premier League | Fulham2–1BrightonRegular Season - 23 | D |
| 31 de gen. | Premier League | Brighton1–1EvertonRegular Season - 24 | E |
| febrer del 202608 de febr. | Premier League | Brighton0–1Crystal PalaceRegular Season - 25 | D |
| 11 de febr. | Premier League | Aston Villa1–0BrightonRegular Season - 26 | D |
| 21 de febr. | Premier League | Brentford0–2BrightonRegular Season - 27 | V |
| març del 202601 de març | Premier League | Brighton2–1Nottingham ForestRegular Season - 28 | V |
| 04 de març | Premier League | Brighton0–1ArsenalRegular Season - 29 | D |
| 14 de març | Premier League | Sunderland0–1BrightonRegular Season - 30 | V |
| 21 de març | Premier League | Brighton2–1LiverpoolRegular Season - 31 | V |
| abril del 202611 d’abr. | Premier League | Burnley0–2BrightonRegular Season - 32 | V |
| 18 d’abr. | Premier League | Tottenham2–2BrightonRegular Season - 33 | E |
| 21 d’abr. | Premier League | Brighton3–0ChelseaRegular Season - 34 | V |
| maig del 202602 de maig | Premier League | Newcastle3–1BrightonRegular Season - 35 | D |
| 09 de maig | Premier League | Brighton3–0WolvesRegular Season - 36 | V |
| 17 de maig | Premier League | Leeds1–0BrightonRegular Season - 37 | D |
| 24 de maig | Premier League | Brighton0–3Manchester UnitedRegular Season - 38 | D |
