| juliol del 202526 de jul. |  Jupiler Pro League | Dender 0–0 Cercle BruggeRegular Season - 1 | E |
| agost del 202503 d’ag. | Jupiler Pro League | Cercle Brugge0–2 AnderlechtRegular Season - 2 | D |
| 09 d’ag. | Jupiler Pro League | Club Brugge KV 2–0Cercle BruggeRegular Season - 3 | D |
| 17 d’ag. | Jupiler Pro League | Cercle Brugge4–1 KVC WesterloRegular Season - 4 | V |
| 23 d’ag. | Jupiler Pro League | Standard Liege 0–3Cercle BruggeRegular Season - 5 | V |
| 29 d’ag. | Jupiler Pro League | Cercle Brugge1–1 St. TruidenRegular Season - 6 | E |
| setembre del 202514 de set. | Jupiler Pro League | Cercle Brugge2–3 CharleroiRegular Season - 7 | D |
| 21 de set. | Jupiler Pro League | KV Mechelen 0–0Cercle BruggeRegular Season - 8 | E |
| 28 de set. | Jupiler Pro League | Cercle Brugge2–4 GentRegular Season - 9 | D |
| octubre del 202504 d’oct. | Jupiler Pro League | Antwerp 1–1Cercle BruggeRegular Season - 10 | E |
| 19 d’oct. | Jupiler Pro League | Cercle Brugge2–2 GenkRegular Season - 11 | E |
| 26 d’oct. | Jupiler Pro League | Cercle Brugge1–1 Zulte WaregemRegular Season - 12 | E |
| novembre del 202502 de nov. | Jupiler Pro League | RAAL La Louvière 2–1Cercle BruggeRegular Season - 13 | D |
| 08 de nov. | Jupiler Pro League | Cercle Brugge1–2 OH LeuvenRegular Season - 14 | D |
| 22 de nov. | Jupiler Pro League | Union St. Gilloise 2–0Cercle BruggeRegular Season - 15 | D |
| 29 de nov. | Jupiler Pro League | Zulte Waregem1–1Cercle BruggeRegular Season - 16 | E |
| desembre del 202506 de des. | Jupiler Pro League | Cercle Brugge1–2Standard LiegeRegular Season - 17 | D |
| 13 de des. | Jupiler Pro League | Cercle Brugge2–3KV MechelenRegular Season - 18 | D |
| 21 de des. | Jupiler Pro League | OH Leuven0–2Cercle BruggeRegular Season - 19 | V |
| 26 de des. | Jupiler Pro League | Cercle Brugge1–1Union St. GilloiseRegular Season - 20 | E |
| gener del 202617 de gen. | Jupiler Pro League | KVC Westerlo0–2Cercle BruggeRegular Season - 21 | V |
| 25 de gen. | Jupiler Pro League | Genk1–1Cercle BruggeRegular Season - 22 | E |
| 31 de gen. | Jupiler Pro League | Cercle Brugge0–4AntwerpRegular Season - 23 | D |
| febrer del 202607 de febr. | Jupiler Pro League | Charleroi3–4Cercle BruggeRegular Season - 24 | V |
| 15 de febr. | Jupiler Pro League | Cercle Brugge1–2Club Brugge KVRegular Season - 25 | D |
| 20 de febr. | Jupiler Pro League | Gent0–1Cercle BruggeRegular Season - 26 | V |
| març del 202601 de març | Jupiler Pro League | Cercle Brugge0–0DenderRegular Season - 27 | E |
| 08 de març | Jupiler Pro League | St. Truiden2–1Cercle BruggeRegular Season - 28 | D |
| 15 de març | Jupiler Pro League | Cercle Brugge1–3RAAL La LouvièreRegular Season - 29 | D |
| 22 de març | Jupiler Pro League | Anderlecht2–3Cercle BruggeRegular Season - 30 | V |
| abril del 202604 d’abr. | Jupiler Pro League | Zulte Waregem2–2Cercle BruggeRelegation Group - 31 | E |
| 11 d’abr. | Jupiler Pro League | Cercle Brugge3–0RAAL La LouvièreRelegation Group - 32 | V |
| 19 d’abr. | Jupiler Pro League | Dender1–4Cercle BruggeRelegation Group - 33 | V |
| 24 d’abr. | Jupiler Pro League | Cercle Brugge2–1DenderRelegation Group - 34 | V |
| maig del 202601 de maig | Jupiler Pro League | Cercle Brugge2–3Zulte WaregemRelegation Group - 35 | D |
| 09 de maig | Jupiler Pro League | RAAL La Louvière4–1Cercle BruggeRelegation Group - 36 | D |
