| juliol del 202625 de jul. |  Premier Liga | Spartak Moscow 3–0 Rodina MoskvaRegular Season - 1 | V |
| agost del 202602 d’ag. | Premier Liga | Akhmat 19:30Spartak MoscowRegular Season - 2 | — |
| 09 d’ag. | Premier Liga | Spartak Moscow19:30 FC KrasnodarRegular Season - 3 | — |
| 16 d’ag. | Premier Liga | Baltika 18:30Spartak MoscowRegular Season - 4 | — |
| 23 d’ag. | Premier Liga | Spartak Moscow19:00 ZenitRegular Season - 5 | — |
| 30 d’ag. | Premier Liga | Spartak Moscow16:30 FC OrenburgRegular Season - 6 | — |
| setembre del 202606 de set. | Premier Liga | Dynamo 17:30Spartak MoscowRegular Season - 7 | — |
| 13 de set. | Premier Liga | Spartak Moscow16:00 FC RostovRegular Season - 8 | — |
| 16 de set. | Premier Liga | Spartak Moscow17:30 FakelRegular Season - 9 | — |
| octubre del 202610 d’oct. | Premier Liga | Krylia Sovetov 17:00Spartak MoscowRegular Season - 10 | — |
| 17 d’oct. | Premier Liga | Spartak Moscow17:00 RubinRegular Season - 11 | — |
| 24 d’oct. | Premier Liga | CSKA Moscow 17:00Spartak MoscowRegular Season - 12 | — |
| 31 d’oct. | Premier Liga | Lokomotiv 17:00Spartak MoscowRegular Season - 13 | — |
| novembre del 202607 de nov. | Premier Liga | Spartak Moscow17:00 AkronRegular Season - 14 | — |
| 21 de nov. | Premier Liga | Dinamo Makhachkala 17:00Spartak MoscowRegular Season - 15 | — |
| 28 de nov. | Premier Liga | Fakel17:00Spartak MoscowRegular Season - 16 | — |
| desembre del 202605 de des. | Premier Liga | Spartak Moscow17:00DynamoRegular Season - 17 | — |
| febrer del 202727 de febr. | Premier Liga | FC Krasnodar17:00Spartak MoscowRegular Season - 18 | — |
| març del 202706 de març | Premier Liga | Akron17:00Spartak MoscowRegular Season - 19 | — |
| 13 de març | Premier Liga | Spartak Moscow17:00AkhmatRegular Season - 20 | — |
| 20 de març | Premier Liga | Rubin17:00Spartak MoscowRegular Season - 21 | — |
| abril del 202703 d’abr. | Premier Liga | Spartak Moscow17:00Dinamo MakhachkalaRegular Season - 22 | — |
| 10 d’abr. | Premier Liga | FC Orenburg17:00Spartak MoscowRegular Season - 23 | — |
| 17 d’abr. | Premier Liga | Spartak Moscow17:00CSKA MoscowRegular Season - 24 | — |
| 24 d’abr. | Premier Liga | Rodina Moskva17:00Spartak MoscowRegular Season - 25 | — |
| maig del 202701 de maig | Premier Liga | Spartak Moscow17:00BaltikaRegular Season - 26 | — |
| 08 de maig | Premier Liga | Spartak Moscow17:00LokomotivRegular Season - 27 | — |
| 15 de maig | Premier Liga | Zenit17:00Spartak MoscowRegular Season - 28 | — |
| 22 de maig | Premier Liga | Spartak Moscow17:00Krylia SovetovRegular Season - 29 | — |
| 29 de maig | Premier Liga | FC Rostov17:00Spartak MoscowRegular Season - 30 | — |
