| agost del 202516 d’ag. |  Premier League | Sunderland 3–0 West HamRegular Season - 1 | D |
| 22 d’ag. | Premier League | West Ham1–5 ChelseaRegular Season - 2 | D |
| 31 d’ag. | Premier League | Nottingham Forest 0–3West HamRegular Season - 3 | V |
| setembre del 202513 de set. | Premier League | West Ham0–3 TottenhamRegular Season - 4 | D |
| 20 de set. | Premier League | West Ham1–2 Crystal PalaceRegular Season - 5 | D |
| 29 de set. | Premier League | Everton 1–1West HamRegular Season - 6 | E |
| octubre del 202504 d’oct. | Premier League | Arsenal 2–0West HamRegular Season - 7 | D |
| 20 d’oct. | Premier League | West Ham0–2 BrentfordRegular Season - 8 | D |
| 24 d’oct. | Premier League | Leeds 2–1West HamRegular Season - 9 | D |
| novembre del 202502 de nov. | Premier League | West Ham3–1 NewcastleRegular Season - 10 | V |
| 08 de nov. | Premier League | West Ham3–2 BurnleyRegular Season - 11 | V |
| 22 de nov. | Premier League | Bournemouth 2–2West HamRegular Season - 12 | E |
| 30 de nov. | Premier League | West Ham0–2 LiverpoolRegular Season - 13 | D |
| desembre del 202504 de des. | Premier League | Manchester United 1–1West HamRegular Season - 14 | E |
| 07 de des. | Premier League | Brighton 1–1West HamRegular Season - 15 | E |
| 14 de des. | Premier League | West Ham2–3 Aston VillaRegular Season - 16 | D |
| 20 de des. | Premier League | Manchester City 3–0West HamRegular Season - 17 | D |
| 27 de des. | Premier League | West Ham0–1 FulhamRegular Season - 18 | D |
| 30 de des. | Premier League | West Ham2–2BrightonRegular Season - 19 | E |
| gener del 202603 de gen. | Premier League | Wolves 3–0West HamRegular Season - 20 | D |
| 06 de gen. | Premier League | West Ham1–2Nottingham ForestRegular Season - 21 | D |
| 17 de gen. | Premier League | Tottenham1–2West HamRegular Season - 22 | V |
| 24 de gen. | Premier League | West Ham3–1SunderlandRegular Season - 23 | V |
| 31 de gen. | Premier League | Chelsea3–2West HamRegular Season - 24 | D |
| febrer del 202607 de febr. | Premier League | Burnley0–2West HamRegular Season - 25 | V |
| 10 de febr. | Premier League | West Ham1–1Manchester UnitedRegular Season - 26 | E |
| 21 de febr. | Premier League | West Ham0–0BournemouthRegular Season - 27 | E |
| 28 de febr. | Premier League | Liverpool5–2West HamRegular Season - 28 | D |
| març del 202604 de març | Premier League | Fulham0–1West HamRegular Season - 29 | V |
| 14 de març | Premier League | West Ham1–1Manchester CityRegular Season - 30 | E |
| 22 de març | Premier League | Aston Villa2–0West HamRegular Season - 31 | D |
| abril del 202610 d’abr. | Premier League | West Ham4–0WolvesRegular Season - 32 | V |
| 20 d’abr. | Premier League | Crystal Palace0–0West HamRegular Season - 33 | E |
| 25 d’abr. | Premier League | West Ham2–1EvertonRegular Season - 34 | V |
| maig del 202602 de maig | Premier League | Brentford3–0West HamRegular Season - 35 | D |
| 10 de maig | Premier League | West Ham0–1ArsenalRegular Season - 36 | D |
| 17 de maig | Premier League | Newcastle3–1West HamRegular Season - 37 | D |
| 24 de maig | Premier League | West Ham3–0LeedsRegular Season - 38 | V |
