| août 202516 août |  Premier League | Aston Villa 0–0 NewcastleRegular Season - 1 | N |
| 25 août | Premier League | Newcastle2–3 LiverpoolRegular Season - 2 | D |
| 30 août | Premier League | Leeds 0–0NewcastleRegular Season - 3 | N |
| septembre 202513 sept. | Premier League | Newcastle1–0 WolvesRegular Season - 4 | V |
| 18 sept. |  Champions League | Newcastle1–2 BarcelonaLeague Stage - 1 | D |
| 21 sept. | Premier League | Bournemouth 0–0NewcastleRegular Season - 5 | N |
| 28 sept. | Premier League | Newcastle1–2 ArsenalRegular Season - 6 | D |
| octobre 202501 oct. | Champions League | Union St. Gilloise 0–4NewcastleLeague Stage - 2 | V |
| 05 oct. | Premier League | Newcastle2–0 Nottingham ForestRegular Season - 7 | V |
| 18 oct. | Premier League | Brighton 2–1NewcastleRegular Season - 8 | D |
| 21 oct. | Champions League | Newcastle3–0 BenficaLeague Stage - 3 | V |
| 25 oct. | Premier League | Newcastle2–1 FulhamRegular Season - 9 | V |
| novembre 202502 nov. | Premier League | West Ham 3–1NewcastleRegular Season - 10 | D |
| 05 nov. | Champions League | Newcastle2–0 Athletic ClubLeague Stage - 4 | V |
| 09 nov. | Premier League | Brentford 3–1NewcastleRegular Season - 11 | D |
| 22 nov. | Premier League | Newcastle2–1 Manchester CityRegular Season - 12 | V |
| 25 nov. | Champions League | Marseille 2–1NewcastleLeague Stage - 5 | D |
| 29 nov. | Premier League | Everton 1–4NewcastleRegular Season - 13 | V |
| décembre 202502 déc. | Premier League | Newcastle2–2 TottenhamRegular Season - 14 | N |
| 06 déc. | Premier League | Newcastle2–1 BurnleyRegular Season - 15 | V |
| 10 déc. | Champions League | Bayer Leverkusen 2–2NewcastleLeague Stage - 6 | N |
| 14 déc. | Premier League | Sunderland 1–0NewcastleRegular Season - 16 | D |
| 20 déc. | Premier League | Newcastle2–2 ChelseaRegular Season - 17 | N |
| 26 déc. | Premier League | Manchester United 1–0NewcastleRegular Season - 18 | D |
| 30 déc. | Premier League | Burnley1–3NewcastleRegular Season - 19 | V |
| janvier 202604 janv. | Premier League | Newcastle2–0 Crystal PalaceRegular Season - 20 | V |
| 07 janv. | Premier League | Newcastle4–3LeedsRegular Season - 21 | V |
| 18 janv. | Premier League | Wolves0–0NewcastleRegular Season - 22 | N |
| 21 janv. | Champions League | Newcastle3–0 PSV EindhovenLeague Stage - 7 | V |
| 25 janv. | Premier League | Newcastle0–2Aston VillaRegular Season - 23 | D |
| 28 janv. | Champions League | Paris Saint Germain 1–1NewcastleLeague Stage - 8 | N |
| 31 janv. | Premier League | Liverpool4–1NewcastleRegular Season - 24 | D |
| février 202607 févr. | Premier League | Newcastle2–3BrentfordRegular Season - 25 | D |
| 10 févr. | Premier League | Tottenham1–2NewcastleRegular Season - 26 | V |
| 18 févr. | Champions League | Qarabag 1–6NewcastleRound of 32 | V |
| 21 févr. | Premier League | Manchester City2–1NewcastleRegular Season - 27 | D |
| 24 févr. | Champions League | Newcastle3–2QarabagRound of 32 | V |
| 28 févr. | Premier League | Newcastle2–3EvertonRegular Season - 28 | D |
| mars 202604 mars | Premier League | Newcastle2–1Manchester UnitedRegular Season - 29 | V |
| 10 mars | Champions League | Newcastle1–1BarcelonaRound of 16 | N |
| 14 mars | Premier League | Chelsea0–1NewcastleRegular Season - 30 | V |
| 18 mars | Champions League | Barcelona7–2NewcastleRound of 16 | D |
| 22 mars | Premier League | Newcastle1–2SunderlandRegular Season - 31 | D |
| avril 202612 avr. | Premier League | Crystal Palace2–1NewcastleRegular Season - 32 | D |
| 18 avr. | Premier League | Newcastle1–2BournemouthRegular Season - 33 | D |
| 25 avr. | Premier League | Arsenal1–0NewcastleRegular Season - 34 | D |
| mai 202602 mai | Premier League | Newcastle3–1BrightonRegular Season - 35 | V |
| 10 mai | Premier League | Nottingham Forest1–1NewcastleRegular Season - 36 | N |
| 17 mai | Premier League | Newcastle3–1West HamRegular Season - 37 | V |
| 24 mai | Premier League | Fulham2–0NewcastleRegular Season - 38 | D |
