| August 2025Aug 23 |  Serie A | AS Roma 1–0 BolognaRegular Season - 1 | W |
| Aug 30 | Serie A | Pisa 0–1AS RomaRegular Season - 2 | W |
| September 2025Sep 14 | Serie A | AS Roma0–1 TorinoRegular Season - 3 | L |
| Sep 21 | Serie A | Lazio 0–1AS RomaRegular Season - 4 | W |
| Sep 24 |  Europa League | Nice 1–2AS RomaLeague Stage - 1 | W |
| Sep 28 | Serie A | AS Roma2–0 Hellas VeronaRegular Season - 5 | W |
| October 2025Oct 02 | Europa League | AS Roma0–1 LilleLeague Stage - 2 | L |
| Oct 05 | Serie A | Fiorentina 1–2AS RomaRegular Season - 6 | W |
| Oct 18 | Serie A | AS Roma0–1 InterRegular Season - 7 | L |
| Oct 23 | Europa League | AS Roma1–2 PlzenLeague Stage - 3 | L |
| Oct 26 | Serie A | Sassuolo 0–1AS RomaRegular Season - 8 | W |
| Oct 29 | Serie A | AS Roma2–1 ParmaRegular Season - 9 | W |
| November 2025Nov 02 | Serie A | AC Milan 1–0AS RomaRegular Season - 10 | L |
| Nov 06 | Europa League | Rangers 0–2AS RomaLeague Stage - 4 | W |
| Nov 09 | Serie A | AS Roma2–0 UdineseRegular Season - 11 | W |
| Nov 23 | Serie A | Cremonese 1–3AS RomaRegular Season - 12 | W |
| Nov 27 | Europa League | AS Roma2–1 FC MidtjyllandLeague Stage - 5 | W |
| Nov 30 | Serie A | AS Roma0–1 NapoliRegular Season - 13 | L |
| December 2025Dec 07 | Serie A | Cagliari 1–0AS RomaRegular Season - 14 | L |
| Dec 11 | Europa League | Celtic 0–3AS RomaLeague Stage - 6 | W |
| Dec 15 | Serie A | AS Roma1–0 ComoRegular Season - 15 | W |
| Dec 20 | Serie A | Juventus 2–1AS RomaRegular Season - 16 | L |
| Dec 29 | Serie A | AS Roma3–1 GenoaRegular Season - 17 | W |
| January 2026Jan 03 | Serie A | Atalanta 1–0AS RomaRegular Season - 18 | L |
| Jan 06 | Serie A | Lecce 0–2AS RomaRegular Season - 19 | W |
| Jan 10 | Serie A | AS Roma2–0SassuoloRegular Season - 20 | W |
| Jan 18 | Serie A | Torino0–2AS RomaRegular Season - 21 | W |
| Jan 22 | Europa League | AS Roma2–0 VfB StuttgartLeague Stage - 7 | W |
| Jan 25 | Serie A | AS Roma1–1AC MilanRegular Season - 22 | D |
| Jan 29 | Europa League | Panathinaikos 1–1AS RomaLeague Stage - 8 | D |
| February 2026Feb 02 | Serie A | Udinese1–0AS RomaRegular Season - 23 | L |
| Feb 09 | Serie A | AS Roma2–0CagliariRegular Season - 24 | W |
| Feb 15 | Serie A | Napoli2–2AS RomaRegular Season - 25 | D |
| Feb 22 | Serie A | AS Roma3–0CremoneseRegular Season - 26 | W |
| March 2026Mar 01 | Serie A | AS Roma3–3JuventusRegular Season - 27 | D |
| Mar 08 | Serie A | Genoa2–1AS RomaRegular Season - 28 | L |
| Mar 12 | Europa League | Bologna1–1AS RomaRound of 16 | D |
| Mar 15 | Serie A | Como2–1AS RomaRegular Season - 29 | L |
| Mar 19 | Europa League | AS Roma3–4BolognaRound of 16 | L |
| Mar 22 | Serie A | AS Roma1–0LecceRegular Season - 30 | W |
| April 2026Apr 05 | Serie A | Inter5–2AS RomaRegular Season - 31 | L |
| Apr 10 | Serie A | AS Roma3–0PisaRegular Season - 32 | W |
| Apr 18 | Serie A | AS Roma1–1AtalantaRegular Season - 33 | D |
| Apr 25 | Serie A | Bologna0–2AS RomaRegular Season - 34 | W |
| May 2026May 04 | Serie A | AS Roma4–0FiorentinaRegular Season - 35 | W |
| May 10 | Serie A | Parma2–3AS RomaRegular Season - 36 | W |
| May 17 | Serie A | AS Roma2–0LazioRegular Season - 37 | W |
| May 24 | Serie A | Hellas Verona0–2AS RomaRegular Season - 38 | W |
