| August 2022Aug 06 |  Ligue 1 | Strasbourg 1–2 MonacoRegular Season - 1 | W |
| Aug 13 | Ligue 1 | Monaco1–1 RennesRegular Season - 2 | D |
| Aug 20 | Ligue 1 | Monaco1–4 LensRegular Season - 3 | L |
| Aug 28 | Ligue 1 | Paris Saint Germain 1–1MonacoRegular Season - 4 | D |
| Aug 31 | Ligue 1 | Monaco2–4 Estac TroyesRegular Season - 5 | L |
| September 2022Sep 04 | Ligue 1 | Nice 0–1MonacoRegular Season - 6 | W |
| Sep 11 | Ligue 1 | Monaco2–1 LyonRegular Season - 7 | W |
| Sep 18 | Ligue 1 | Reims 0–3MonacoRegular Season - 8 | W |
| October 2022Oct 02 | Ligue 1 | Monaco4–1 NantesRegular Season - 9 | W |
| Oct 09 | Ligue 1 | Montpellier 0–2MonacoRegular Season - 10 | W |
| Oct 16 | Ligue 1 | Monaco1–1 Clermont FootRegular Season - 11 | D |
| Oct 23 | Ligue 1 | Lille 4–3MonacoRegular Season - 12 | L |
| Oct 30 | Ligue 1 | Monaco2–0 AngersRegular Season - 13 | W |
| November 2022Nov 06 | Ligue 1 | Toulouse 0–2MonacoRegular Season - 14 | W |
| Nov 13 | Ligue 1 | Monaco2–3 MarseilleRegular Season - 15 | L |
| December 2022Dec 28 | Ligue 1 | Auxerre 2–3MonacoRegular Season - 16 | W |
| January 2023Jan 01 | Ligue 1 | Monaco1–0 Stade Brestois 29Regular Season - 17 | W |
| Jan 11 | Ligue 1 | Lorient 2–2MonacoRegular Season - 18 | D |
| Jan 15 | Ligue 1 | Monaco7–1 AjaccioRegular Season - 19 | W |
| Jan 28 | Ligue 1 | Marseille1–1MonacoRegular Season - 20 | D |
| February 2023Feb 01 | Ligue 1 | Monaco3–2AuxerreRegular Season - 21 | W |
| Feb 05 | Ligue 1 | Clermont Foot0–2MonacoRegular Season - 22 | W |
| Feb 11 | Ligue 1 | Monaco3–1Paris Saint GermainRegular Season - 23 | W |
| Feb 19 | Ligue 1 | Stade Brestois 291–2MonacoRegular Season - 24 | W |
| Feb 26 | Ligue 1 | Monaco0–3NiceRegular Season - 25 | L |
| March 2023Mar 05 | Ligue 1 | Estac Troyes2–2MonacoRegular Season - 26 | D |
| Mar 12 | Ligue 1 | Monaco0–1ReimsRegular Season - 27 | L |
| Mar 19 | Ligue 1 | Ajaccio0–2MonacoRegular Season - 28 | W |
| April 2023Apr 02 | Ligue 1 | Monaco4–3StrasbourgRegular Season - 29 | W |
| Apr 09 | Ligue 1 | Nantes2–2MonacoRegular Season - 30 | D |
| Apr 16 | Ligue 1 | Monaco3–1LorientRegular Season - 31 | W |
| Apr 22 | Ligue 1 | Lens3–0MonacoRegular Season - 32 | L |
| Apr 30 | Ligue 1 | Monaco0–4MontpellierRegular Season - 33 | L |
| May 2023May 07 | Ligue 1 | Angers1–2MonacoRegular Season - 34 | W |
| May 14 | Ligue 1 | Monaco0–0LilleRegular Season - 35 | D |
| May 19 | Ligue 1 | Lyon3–1MonacoRegular Season - 36 | L |
| May 27 | Ligue 1 | Rennes2–0MonacoRegular Season - 37 | L |
| June 2023Jun 03 | Ligue 1 | Monaco1–2ToulouseRegular Season - 38 | L |
