| January 2025Jan 26 |  Liga Profesional Argentina | Platense 1–1 River Plate1st Phase - 1 | D |
| Jan 30 | Liga Profesional Argentina | River Plate1–0 Instituto Cordoba1st Phase - 2 | W |
| February 2025Feb 02 | Liga Profesional Argentina | San Lorenzo 0–0River Plate1st Phase - 3 | D |
| Feb 09 | Liga Profesional Argentina | River Plate2–0 Independiente1st Phase - 4 | W |
| Feb 13 | Liga Profesional Argentina | Godoy Cruz 0–0River Plate1st Phase - 5 | D |
| Feb 16 | Liga Profesional Argentina | River Plate1–0 Lanus1st Phase - 6 | W |
| Feb 23 | Liga Profesional Argentina | San Martin S.J. 0–2River Plate1st Phase - 7 | W |
| March 2025Mar 01 | Liga Profesional Argentina | River Plate0–2 Estudiantes L.P.1st Phase - 8 | L |
| Mar 09 | Liga Profesional Argentina | River Plate1–0 Atletico Tucuman1st Phase - 9 | W |
| Mar 15 | Liga Profesional Argentina | Deportivo Riestra 0–0River Plate1st Phase - 10 | D |
| Mar 20 |  Copa Argentina | River Plate2–0 Ciudad de Bolívar1st Round | W |
| Mar 30 | Liga Profesional Argentina | River Plate2–2 Rosario Central1st Phase - 11 | D |
| April 2025Apr 03 |  Copa Libertadores | Universitario 0–1River PlateGroup Stage - 1 | W |
| Apr 06 | Liga Profesional Argentina | Sarmiento Junin 1–1River Plate1st Phase - 12 | D |
| Apr 09 | Copa Libertadores | River Plate0–0 Barcelona SCGroup Stage - 2 | D |
| Apr 14 | Liga Profesional Argentina | River Plate1–1 Talleres Cordoba1st Phase - 13 | D |
| Apr 18 | Liga Profesional Argentina | Gimnasia L.P. 0–3River Plate1st Phase - 14 | W |
| Apr 24 | Copa Libertadores | Independiente del Valle 2–2River PlateGroup Stage - 3 | D |
| Apr 27 | Liga Profesional Argentina | River Plate2–1 Boca Juniors1st Phase - 15 | W |
| May 2025May 05 | Liga Profesional Argentina | River Plate4–1 Velez Sarsfield1st Phase - 16 | W |
| May 09 | Copa Libertadores | Barcelona SC2–3River PlateGroup Stage - 4 | W |
| May 13 | Liga Profesional Argentina | River Plate3–0 Barracas Central1st Phase - 8th Finals | W |
| May 16 | Copa Libertadores | River Plate6–2Independiente del ValleGroup Stage - 5 | W |
| May 21 | Liga Profesional Argentina | River Plate1–1Platense1st Phase - Quarter-finals | D |
| May 28 | Copa Libertadores | River Plate1–1UniversitarioGroup Stage - 6 | D |
| June 2025Jun 17 |  Mundial de Clubs | River Plate3–1 UrawaGroup Stage - 1 | W |
| Jun 22 | Mundial de Clubs | River Plate0–0 MonterreyGroup Stage - 2 | D |
| Jun 26 | Mundial de Clubs | Inter 2–0River PlateGroup Stage - 3 | L |
| July 2025Jul 14 | Liga Profesional Argentina | River Plate3–1Platense2nd Phase - 1 | W |
| Jul 20 | Liga Profesional Argentina | Instituto Cordoba0–4River Plate2nd Phase - 2 | W |
| Jul 28 | Liga Profesional Argentina | River Plate0–0San Lorenzo2nd Phase - 3 | D |
| August 2025Aug 03 | Copa Argentina | San Martin Tucuman 0–3River PlateRound of 32 | W |
| Aug 09 | Liga Profesional Argentina | Independiente0–0River Plate2nd Phase - 4 | D |
| Aug 15 | Copa Libertadores | Libertad Asuncion 0–0River PlateRound of 16 | D |
| Aug 17 | Liga Profesional Argentina | River Plate4–2Godoy Cruz2nd Phase - 5 | W |
| Aug 22 | Copa Libertadores | River Plate1–1Libertad AsuncionRound of 16 | D |
| Aug 26 | Liga Profesional Argentina | Lanus1–1River Plate2nd Phase - 6 | D |
| Aug 29 | Copa Argentina | Union Santa Fe 0–0River PlateRound of 16 | D |
| September 2025Sep 01 | Liga Profesional Argentina | River Plate2–0San Martin S.J.2nd Phase - 7 | W |
| Sep 14 | Liga Profesional Argentina | Estudiantes L.P.1–2River Plate2nd Phase - 8 | W |
| Sep 18 | Copa Libertadores | River Plate1–2 PalmeirasQuarter-finals | L |
| Sep 21 | Liga Profesional Argentina | Atletico Tucuman2–0River Plate2nd Phase - 9 | L |
| Sep 25 | Copa Libertadores | Palmeiras3–1River PlateQuarter-finals | L |
| Sep 28 | Liga Profesional Argentina | River Plate1–2Deportivo Riestra2nd Phase - 10 | L |
| October 2025Oct 02 | Copa Argentina | Racing Club 0–1River PlateQuarter-finals | W |
| Oct 06 | Liga Profesional Argentina | Rosario Central2–1River Plate2nd Phase - 11 | L |
| Oct 13 | Liga Profesional Argentina | River Plate0–1Sarmiento Junin2nd Phase - 12 | L |
| Oct 19 | Liga Profesional Argentina | Talleres Cordoba0–2River Plate2nd Phase - 13 | W |
| Oct 25 | Copa Argentina | Independ. Rivadavia 0–0River PlateSemi-finals | D |
| November 2025Nov 03 | Liga Profesional Argentina | River Plate0–1Gimnasia L.P.2nd Phase - 14 | L |
| Nov 09 | Liga Profesional Argentina | Boca Juniors2–0River Plate2nd Phase - 15 | L |
| Nov 16 | Liga Profesional Argentina | Velez Sarsfield0–0River Plate2nd Phase - 16 | D |
| Nov 24 | Liga Profesional Argentina | Racing Club3–2River PlateRound of 16 | L |
