| agost del 202622 d’ag. |  Serie A | Parma 18:45 CagliariRegular Season - 1 | — |
| 30 d’ag. | Serie A | Cagliari18:45 InterRegular Season - 2 | — |
| setembre del 202607 de set. | Serie A | Cagliari16:00 LecceRegular Season - 3 | — |
| 12 de set. | Serie A | Atalanta 18:45CagliariRegular Season - 4 | — |
| 19 de set. | Serie A | Udinese 13:00CagliariRegular Season - 5 | — |
| octubre del 202611 d’oct. | Serie A | Cagliari16:30 JuventusRegular Season - 6 | — |
| 18 d’oct. | Serie A | Monza 16:30CagliariRegular Season - 7 | — |
| 25 d’oct. | Serie A | Cagliari17:30 BolognaRegular Season - 8 | — |
| 28 d’oct. | Serie A | AS Roma 17:30CagliariRegular Season - 9 | — |
| novembre del 202601 de nov. | Serie A | Lazio 17:30CagliariRegular Season - 10 | — |
| 08 de nov. | Serie A | Cagliari17:30 FrosinoneRegular Season - 11 | — |
| 22 de nov. | Serie A | Como 17:30CagliariRegular Season - 12 | — |
| 29 de nov. | Serie A | Cagliari17:30 AC MilanRegular Season - 13 | — |
| desembre del 202606 de des. | Serie A | Fiorentina 17:30CagliariRegular Season - 14 | — |
| 13 de des. | Serie A | Cagliari17:30 VeneziaRegular Season - 15 | — |
| 20 de des. | Serie A | Torino 17:30CagliariRegular Season - 16 | — |
| gener del 202703 de gen. | Serie A | Cagliari17:30 GenoaRegular Season - 17 | — |
| 06 de gen. | Serie A | Napoli 17:30CagliariRegular Season - 18 | — |
| 10 de gen. | Serie A | Cagliari17:30 SassuoloRegular Season - 19 | — |
| 17 de gen. | Serie A | Cagliari17:30ComoRegular Season - 20 | — |
| 24 de gen. | Serie A | Juventus17:30CagliariRegular Season - 21 | — |
| 31 de gen. | Serie A | Cagliari17:30ParmaRegular Season - 22 | — |
| febrer del 202707 de febr. | Serie A | Inter17:30CagliariRegular Season - 23 | — |
| 14 de febr. | Serie A | Cagliari17:30LazioRegular Season - 24 | — |
| 21 de febr. | Serie A | Venezia17:30CagliariRegular Season - 25 | — |
| 28 de febr. | Serie A | Cagliari17:30UdineseRegular Season - 26 | — |
| març del 202707 de març | Serie A | AC Milan17:30CagliariRegular Season - 27 | — |
| 14 de març | Serie A | Cagliari17:30FiorentinaRegular Season - 28 | — |
| 21 de març | Serie A | Sassuolo17:30CagliariRegular Season - 29 | — |
| abril del 202704 d’abr. | Serie A | Cagliari16:30NapoliRegular Season - 30 | — |
| 11 d’abr. | Serie A | Cagliari16:30AtalantaRegular Season - 31 | — |
| 18 d’abr. | Serie A | Bologna16:30CagliariRegular Season - 32 | — |
| 25 d’abr. | Serie A | Cagliari16:30MonzaRegular Season - 33 | — |
| maig del 202702 de maig | Serie A | Lecce16:30CagliariRegular Season - 34 | — |
| 09 de maig | Serie A | Genoa16:30CagliariRegular Season - 35 | — |
| 16 de maig | Serie A | Cagliari16:30TorinoRegular Season - 36 | — |
| 23 de maig | Serie A | Frosinone16:30CagliariRegular Season - 37 | — |
| 30 de maig | Serie A | Cagliari16:30AS RomaRegular Season - 38 | — |
