| agosto de 202524 ago |  Serie A | Cagliari 1–1 FiorentinaRegular Season - 1 | E |
| 30 ago | Serie A | Napoli 1–0CagliariRegular Season - 2 | D |
| septiembre de 202513 sept | Serie A | Cagliari2–0 ParmaRegular Season - 3 | V |
| 19 sept | Serie A | Lecce 1–2CagliariRegular Season - 4 | V |
| 27 sept | Serie A | Cagliari0–2 InterRegular Season - 5 | D |
| octubre de 202505 oct | Serie A | Udinese 1–1CagliariRegular Season - 6 | E |
| 19 oct | Serie A | Cagliari0–2 BolognaRegular Season - 7 | D |
| 26 oct | Serie A | Hellas Verona 2–2CagliariRegular Season - 8 | E |
| 30 oct | Serie A | Cagliari1–2 SassuoloRegular Season - 9 | D |
| noviembre de 202503 nov | Serie A | Lazio 2–0CagliariRegular Season - 10 | D |
| 08 nov | Serie A | Como 0–0CagliariRegular Season - 11 | E |
| 22 nov | Serie A | Cagliari3–3 GenoaRegular Season - 12 | E |
| 29 nov | Serie A | Juventus 2–1CagliariRegular Season - 13 | D |
| diciembre de 202507 dic | Serie A | Cagliari1–0 AS RomaRegular Season - 14 | V |
| 13 dic | Serie A | Atalanta 2–1CagliariRegular Season - 15 | D |
| 21 dic | Serie A | Cagliari2–2 PisaRegular Season - 16 | E |
| 27 dic | Serie A | Torino 1–2CagliariRegular Season - 17 | V |
| enero de 202602 ene | Serie A | Cagliari0–1 AC MilanRegular Season - 18 | D |
| 08 ene | Serie A | Cremonese 2–2CagliariRegular Season - 19 | E |
| 12 ene | Serie A | Genoa3–0CagliariRegular Season - 20 | D |
| 17 ene | Serie A | Cagliari1–0JuventusRegular Season - 21 | V |
| 24 ene | Serie A | Fiorentina1–2CagliariRegular Season - 22 | V |
| 31 ene | Serie A | Cagliari4–0Hellas VeronaRegular Season - 23 | V |
| febrero de 202609 feb | Serie A | AS Roma2–0CagliariRegular Season - 24 | D |
| 16 feb | Serie A | Cagliari0–2LecceRegular Season - 25 | D |
| 21 feb | Serie A | Cagliari0–0LazioRegular Season - 26 | E |
| 27 feb | Serie A | Parma1–1CagliariRegular Season - 27 | E |
| marzo de 202607 mar | Serie A | Cagliari1–2ComoRegular Season - 28 | D |
| 15 mar | Serie A | Pisa3–1CagliariRegular Season - 29 | D |
| 20 mar | Serie A | Cagliari0–1NapoliRegular Season - 30 | D |
| abril de 202604 abr | Serie A | Sassuolo2–1CagliariRegular Season - 31 | D |
| 11 abr | Serie A | Cagliari1–0CremoneseRegular Season - 32 | V |
| 17 abr | Serie A | Inter3–0CagliariRegular Season - 33 | D |
| 27 abr | Serie A | Cagliari3–2AtalantaRegular Season - 34 | V |
| mayo de 202603 may | Serie A | Bologna0–0CagliariRegular Season - 35 | E |
| 09 may | Serie A | Cagliari0–2UdineseRegular Season - 36 | D |
| 17 may | Serie A | Cagliari2–1TorinoRegular Season - 37 | V |
| 24 may | Serie A | AC Milan1–2CagliariRegular Season - 38 | V |
