| agosto de 202622 ago |  Serie A | Parma 20:45 CagliariRegular Season - 1 | — |
| 30 ago | Serie A | Cagliari20:45 InterRegular Season - 2 | — |
| septiembre de 202607 sept | Serie A | Cagliari18:00 LecceRegular Season - 3 | — |
| 12 sept | Serie A | Atalanta 20:45CagliariRegular Season - 4 | — |
| 19 sept | Serie A | Udinese 15:00CagliariRegular Season - 5 | — |
| octubre de 202611 oct | Serie A | Cagliari18:30 JuventusRegular Season - 6 | — |
| 18 oct | Serie A | Monza 18:30CagliariRegular Season - 7 | — |
| 25 oct | Serie A | Cagliari18:30 BolognaRegular Season - 8 | — |
| 28 oct | Serie A | AS Roma 18:30CagliariRegular Season - 9 | — |
| noviembre de 202601 nov | Serie A | Lazio 18:30CagliariRegular Season - 10 | — |
| 08 nov | Serie A | Cagliari18:30 FrosinoneRegular Season - 11 | — |
| 22 nov | Serie A | Como 18:30CagliariRegular Season - 12 | — |
| 29 nov | Serie A | Cagliari18:30 AC MilanRegular Season - 13 | — |
| diciembre de 202606 dic | Serie A | Fiorentina 18:30CagliariRegular Season - 14 | — |
| 13 dic | Serie A | Cagliari18:30 VeneziaRegular Season - 15 | — |
| 20 dic | Serie A | Torino 18:30CagliariRegular Season - 16 | — |
| enero de 202703 ene | Serie A | Cagliari18:30 GenoaRegular Season - 17 | — |
| 06 ene | Serie A | Napoli 18:30CagliariRegular Season - 18 | — |
| 10 ene | Serie A | Cagliari18:30 SassuoloRegular Season - 19 | — |
| 17 ene | Serie A | Cagliari18:30ComoRegular Season - 20 | — |
| 24 ene | Serie A | Juventus18:30CagliariRegular Season - 21 | — |
| 31 ene | Serie A | Cagliari18:30ParmaRegular Season - 22 | — |
| febrero de 202707 feb | Serie A | Inter18:30CagliariRegular Season - 23 | — |
| 14 feb | Serie A | Cagliari18:30LazioRegular Season - 24 | — |
| 21 feb | Serie A | Venezia18:30CagliariRegular Season - 25 | — |
| 28 feb | Serie A | Cagliari18:30UdineseRegular Season - 26 | — |
| marzo de 202707 mar | Serie A | AC Milan18:30CagliariRegular Season - 27 | — |
| 14 mar | Serie A | Cagliari18:30FiorentinaRegular Season - 28 | — |
| 21 mar | Serie A | Sassuolo18:30CagliariRegular Season - 29 | — |
| abril de 202704 abr | Serie A | Cagliari18:30NapoliRegular Season - 30 | — |
| 11 abr | Serie A | Cagliari18:30AtalantaRegular Season - 31 | — |
| 18 abr | Serie A | Bologna18:30CagliariRegular Season - 32 | — |
| 25 abr | Serie A | Cagliari18:30MonzaRegular Season - 33 | — |
| mayo de 202702 may | Serie A | Lecce18:30CagliariRegular Season - 34 | — |
| 09 may | Serie A | Genoa18:30CagliariRegular Season - 35 | — |
| 16 may | Serie A | Cagliari18:30TorinoRegular Season - 36 | — |
| 23 may | Serie A | Frosinone18:30CagliariRegular Season - 37 | — |
| 30 may | Serie A | Cagliari18:30AS RomaRegular Season - 38 | — |
