| agosto de 202418 ago |  Serie A | Cagliari 0–0 AS RomaRegular Season - 1 | E |
| 26 ago | Serie A | Cagliari1–1 ComoRegular Season - 2 | E |
| 31 ago | Serie A | Lecce 1–0CagliariRegular Season - 3 | D |
| septiembre de 202415 sept | Serie A | Cagliari0–4 NapoliRegular Season - 4 | D |
| 20 sept | Serie A | Cagliari0–2 EmpoliRegular Season - 5 | D |
| 30 sept | Serie A | Parma 2–3CagliariRegular Season - 6 | V |
| octubre de 202406 oct | Serie A | Juventus 1–1CagliariRegular Season - 7 | E |
| 20 oct | Serie A | Cagliari3–2 TorinoRegular Season - 8 | V |
| 25 oct | Serie A | Udinese 2–0CagliariRegular Season - 9 | D |
| 29 oct | Serie A | Cagliari0–2 BolognaRegular Season - 10 | D |
| noviembre de 202404 nov | Serie A | Lazio 2–1CagliariRegular Season - 11 | D |
| 09 nov | Serie A | Cagliari3–3 AC MilanRegular Season - 12 | E |
| 24 nov | Serie A | Genoa 2–2CagliariRegular Season - 13 | E |
| 29 nov | Serie A | Cagliari1–0 Hellas VeronaRegular Season - 14 | V |
| diciembre de 202408 dic | Serie A | Fiorentina 1–0CagliariRegular Season - 15 | D |
| 14 dic | Serie A | Cagliari0–1 AtalantaRegular Season - 16 | D |
| 22 dic | Serie A | Venezia 2–1CagliariRegular Season - 17 | D |
| 28 dic | Serie A | Cagliari0–3 InterRegular Season - 18 | D |
| enero de 202505 ene | Serie A | Monza 1–2CagliariRegular Season - 19 | V |
| 11 ene | Serie A | AC Milan1–1CagliariRegular Season - 20 | E |
| 19 ene | Serie A | Cagliari4–1LecceRegular Season - 21 | V |
| 24 ene | Serie A | Torino2–0CagliariRegular Season - 22 | D |
| febrero de 202503 feb | Serie A | Cagliari1–2LazioRegular Season - 23 | D |
| 09 feb | Serie A | Cagliari2–1ParmaRegular Season - 24 | V |
| 15 feb | Serie A | Atalanta0–0CagliariRegular Season - 25 | E |
| 23 feb | Serie A | Cagliari0–1JuventusRegular Season - 26 | D |
| marzo de 202502 mar | Serie A | Bologna2–1CagliariRegular Season - 27 | D |
| 07 mar | Serie A | Cagliari1–1GenoaRegular Season - 28 | E |
| 16 mar | Serie A | AS Roma1–0CagliariRegular Season - 29 | D |
| 30 mar | Serie A | Cagliari3–0MonzaRegular Season - 30 | V |
| abril de 202506 abr | Serie A | Empoli0–0CagliariRegular Season - 31 | E |
| 12 abr | Serie A | Inter3–1CagliariRegular Season - 32 | D |
| 23 abr | Serie A | Cagliari1–2FiorentinaRegular Season - 33 | D |
| 28 abr | Serie A | Hellas Verona0–2CagliariRegular Season - 34 | V |
| mayo de 202503 may | Serie A | Cagliari1–2UdineseRegular Season - 35 | D |
| 10 may | Serie A | Como3–1CagliariRegular Season - 36 | D |
| 18 may | Serie A | Cagliari3–0VeneziaRegular Season - 37 | V |
| 23 may | Serie A | Napoli2–0CagliariRegular Season - 38 | D |
