| August 2024Aug 18 |  Serie A | Cagliari 0–0 AS RomaRegular Season - 1 | D |
| Aug 26 | Serie A | Cagliari1–1 ComoRegular Season - 2 | D |
| Aug 31 | Serie A | Lecce 1–0CagliariRegular Season - 3 | L |
| September 2024Sep 15 | Serie A | Cagliari0–4 NapoliRegular Season - 4 | L |
| Sep 20 | Serie A | Cagliari0–2 EmpoliRegular Season - 5 | L |
| Sep 30 | Serie A | Parma 2–3CagliariRegular Season - 6 | W |
| October 2024Oct 06 | Serie A | Juventus 1–1CagliariRegular Season - 7 | D |
| Oct 20 | Serie A | Cagliari3–2 TorinoRegular Season - 8 | W |
| Oct 25 | Serie A | Udinese 2–0CagliariRegular Season - 9 | L |
| Oct 29 | Serie A | Cagliari0–2 BolognaRegular Season - 10 | L |
| November 2024Nov 04 | Serie A | Lazio 2–1CagliariRegular Season - 11 | L |
| Nov 09 | Serie A | Cagliari3–3 AC MilanRegular Season - 12 | D |
| Nov 24 | Serie A | Genoa 2–2CagliariRegular Season - 13 | D |
| Nov 29 | Serie A | Cagliari1–0 Hellas VeronaRegular Season - 14 | W |
| December 2024Dec 08 | Serie A | Fiorentina 1–0CagliariRegular Season - 15 | L |
| Dec 14 | Serie A | Cagliari0–1 AtalantaRegular Season - 16 | L |
| Dec 22 | Serie A | Venezia 2–1CagliariRegular Season - 17 | L |
| Dec 28 | Serie A | Cagliari0–3 InterRegular Season - 18 | L |
| January 2025Jan 05 | Serie A | Monza 1–2CagliariRegular Season - 19 | W |
| Jan 11 | Serie A | AC Milan1–1CagliariRegular Season - 20 | D |
| Jan 19 | Serie A | Cagliari4–1LecceRegular Season - 21 | W |
| Jan 24 | Serie A | Torino2–0CagliariRegular Season - 22 | L |
| February 2025Feb 03 | Serie A | Cagliari1–2LazioRegular Season - 23 | L |
| Feb 09 | Serie A | Cagliari2–1ParmaRegular Season - 24 | W |
| Feb 15 | Serie A | Atalanta0–0CagliariRegular Season - 25 | D |
| Feb 23 | Serie A | Cagliari0–1JuventusRegular Season - 26 | L |
| March 2025Mar 02 | Serie A | Bologna2–1CagliariRegular Season - 27 | L |
| Mar 07 | Serie A | Cagliari1–1GenoaRegular Season - 28 | D |
| Mar 16 | Serie A | AS Roma1–0CagliariRegular Season - 29 | L |
| Mar 30 | Serie A | Cagliari3–0MonzaRegular Season - 30 | W |
| April 2025Apr 06 | Serie A | Empoli0–0CagliariRegular Season - 31 | D |
| Apr 12 | Serie A | Inter3–1CagliariRegular Season - 32 | L |
| Apr 23 | Serie A | Cagliari1–2FiorentinaRegular Season - 33 | L |
| Apr 28 | Serie A | Hellas Verona0–2CagliariRegular Season - 34 | W |
| May 2025May 03 | Serie A | Cagliari1–2UdineseRegular Season - 35 | L |
| May 10 | Serie A | Como3–1CagliariRegular Season - 36 | L |
| May 18 | Serie A | Cagliari3–0VeneziaRegular Season - 37 | W |
| May 23 | Serie A | Napoli2–0CagliariRegular Season - 38 | L |
