| août 202418 août |  Serie A | Cagliari 0–0 AS RomaRegular Season - 1 | N |
| 26 août | Serie A | Cagliari1–1 ComoRegular Season - 2 | N |
| 31 août | Serie A | Lecce 1–0CagliariRegular Season - 3 | D |
| septembre 202415 sept. | Serie A | Cagliari0–4 NapoliRegular Season - 4 | D |
| 20 sept. | Serie A | Cagliari0–2 EmpoliRegular Season - 5 | D |
| 30 sept. | Serie A | Parma 2–3CagliariRegular Season - 6 | V |
| octobre 202406 oct. | Serie A | Juventus 1–1CagliariRegular Season - 7 | N |
| 20 oct. | Serie A | Cagliari3–2 TorinoRegular Season - 8 | V |
| 25 oct. | Serie A | Udinese 2–0CagliariRegular Season - 9 | D |
| 29 oct. | Serie A | Cagliari0–2 BolognaRegular Season - 10 | D |
| novembre 202404 nov. | Serie A | Lazio 2–1CagliariRegular Season - 11 | D |
| 09 nov. | Serie A | Cagliari3–3 AC MilanRegular Season - 12 | N |
| 24 nov. | Serie A | Genoa 2–2CagliariRegular Season - 13 | N |
| 29 nov. | Serie A | Cagliari1–0 Hellas VeronaRegular Season - 14 | V |
| décembre 202408 déc. | Serie A | Fiorentina 1–0CagliariRegular Season - 15 | D |
| 14 déc. | Serie A | Cagliari0–1 AtalantaRegular Season - 16 | D |
| 22 déc. | Serie A | Venezia 2–1CagliariRegular Season - 17 | D |
| 28 déc. | Serie A | Cagliari0–3 InterRegular Season - 18 | D |
| janvier 202505 janv. | Serie A | Monza 1–2CagliariRegular Season - 19 | V |
| 11 janv. | Serie A | AC Milan1–1CagliariRegular Season - 20 | N |
| 19 janv. | Serie A | Cagliari4–1LecceRegular Season - 21 | V |
| 24 janv. | Serie A | Torino2–0CagliariRegular Season - 22 | D |
| février 202503 févr. | Serie A | Cagliari1–2LazioRegular Season - 23 | D |
| 09 févr. | Serie A | Cagliari2–1ParmaRegular Season - 24 | V |
| 15 févr. | Serie A | Atalanta0–0CagliariRegular Season - 25 | N |
| 23 févr. | Serie A | Cagliari0–1JuventusRegular Season - 26 | D |
| mars 202502 mars | Serie A | Bologna2–1CagliariRegular Season - 27 | D |
| 07 mars | Serie A | Cagliari1–1GenoaRegular Season - 28 | N |
| 16 mars | Serie A | AS Roma1–0CagliariRegular Season - 29 | D |
| 30 mars | Serie A | Cagliari3–0MonzaRegular Season - 30 | V |
| avril 202506 avr. | Serie A | Empoli0–0CagliariRegular Season - 31 | N |
| 12 avr. | Serie A | Inter3–1CagliariRegular Season - 32 | D |
| 23 avr. | Serie A | Cagliari1–2FiorentinaRegular Season - 33 | D |
| 28 avr. | Serie A | Hellas Verona0–2CagliariRegular Season - 34 | V |
| mai 202503 mai | Serie A | Cagliari1–2UdineseRegular Season - 35 | D |
| 10 mai | Serie A | Como3–1CagliariRegular Season - 36 | D |
| 18 mai | Serie A | Cagliari3–0VeneziaRegular Season - 37 | V |
| 23 mai | Serie A | Napoli2–0CagliariRegular Season - 38 | D |
