| août 202319 août |  Serie A | Empoli 0–1 Hellas VeronaRegular Season - 1 | D |
| 26 août | Serie A | Monza 2–0EmpoliRegular Season - 2 | D |
| septembre 202303 sept. | Serie A | Empoli0–2 JuventusRegular Season - 3 | D |
| 17 sept. | Serie A | AS Roma 7–0EmpoliRegular Season - 4 | D |
| 24 sept. | Serie A | Empoli0–1 InterRegular Season - 5 | D |
| 27 sept. | Serie A | Empoli1–0 SalernitanaRegular Season - 6 | V |
| octobre 202301 oct. | Serie A | Bologna 3–0EmpoliRegular Season - 7 | D |
| 06 oct. | Serie A | Empoli0–0 UdineseRegular Season - 8 | N |
| 23 oct. | Serie A | Fiorentina 0–2EmpoliRegular Season - 9 | V |
| 30 oct. | Serie A | Empoli0–3 AtalantaRegular Season - 10 | D |
| novembre 202306 nov. | Serie A | Frosinone 2–1EmpoliRegular Season - 11 | D |
| 12 nov. | Serie A | Napoli 0–1EmpoliRegular Season - 12 | V |
| 26 nov. | Serie A | Empoli3–4 SassuoloRegular Season - 13 | D |
| décembre 202302 déc. | Serie A | Genoa 1–1EmpoliRegular Season - 14 | N |
| 11 déc. | Serie A | Empoli1–1 LecceRegular Season - 15 | N |
| 16 déc. | Serie A | Torino 1–0EmpoliRegular Season - 16 | D |
| 22 déc. | Serie A | Empoli0–2 LazioRegular Season - 17 | D |
| 30 déc. | Serie A | Cagliari 0–0EmpoliRegular Season - 18 | N |
| janvier 202407 janv. | Serie A | Empoli0–3 AC MilanRegular Season - 19 | D |
| 13 janv. | Serie A | Hellas Verona2–1EmpoliRegular Season - 20 | D |
| 21 janv. | Serie A | Empoli3–0MonzaRegular Season - 21 | V |
| 27 janv. | Serie A | Juventus1–1EmpoliRegular Season - 22 | N |
| février 202403 févr. | Serie A | Empoli0–0GenoaRegular Season - 23 | N |
| 09 févr. | Serie A | Salernitana1–3EmpoliRegular Season - 24 | V |
| 18 févr. | Serie A | Empoli1–1FiorentinaRegular Season - 25 | N |
| 24 févr. | Serie A | Sassuolo2–3EmpoliRegular Season - 26 | V |
| mars 202403 mars | Serie A | Empoli0–1CagliariRegular Season - 27 | D |
| 10 mars | Serie A | AC Milan1–0EmpoliRegular Season - 28 | D |
| 15 mars | Serie A | Empoli0–1BolognaRegular Season - 29 | D |
| avril 202401 avr. | Serie A | Inter2–0EmpoliRegular Season - 30 | D |
| 06 avr. | Serie A | Empoli3–2TorinoRegular Season - 31 | V |
| 13 avr. | Serie A | Lecce1–0EmpoliRegular Season - 32 | D |
| 20 avr. | Serie A | Empoli1–0NapoliRegular Season - 33 | V |
| 28 avr. | Serie A | Atalanta2–0EmpoliRegular Season - 34 | D |
| mai 202405 mai | Serie A | Empoli0–0FrosinoneRegular Season - 35 | N |
| 12 mai | Serie A | Lazio2–0EmpoliRegular Season - 36 | D |
| 19 mai | Serie A | Udinese1–1EmpoliRegular Season - 37 | N |
| 26 mai | Serie A | Empoli2–1AS RomaRegular Season - 38 | V |
