| August 2023Aug 19 |  Serie A | Empoli 0–1 Hellas VeronaRegular Season - 1 | L |
| Aug 26 | Serie A | Monza 2–0EmpoliRegular Season - 2 | L |
| September 2023Sep 03 | Serie A | Empoli0–2 JuventusRegular Season - 3 | L |
| Sep 17 | Serie A | AS Roma 7–0EmpoliRegular Season - 4 | L |
| Sep 24 | Serie A | Empoli0–1 InterRegular Season - 5 | L |
| Sep 27 | Serie A | Empoli1–0 SalernitanaRegular Season - 6 | W |
| October 2023Oct 01 | Serie A | Bologna 3–0EmpoliRegular Season - 7 | L |
| Oct 06 | Serie A | Empoli0–0 UdineseRegular Season - 8 | D |
| Oct 23 | Serie A | Fiorentina 0–2EmpoliRegular Season - 9 | W |
| Oct 30 | Serie A | Empoli0–3 AtalantaRegular Season - 10 | L |
| November 2023Nov 06 | Serie A | Frosinone 2–1EmpoliRegular Season - 11 | L |
| Nov 12 | Serie A | Napoli 0–1EmpoliRegular Season - 12 | W |
| Nov 26 | Serie A | Empoli3–4 SassuoloRegular Season - 13 | L |
| December 2023Dec 02 | Serie A | Genoa 1–1EmpoliRegular Season - 14 | D |
| Dec 11 | Serie A | Empoli1–1 LecceRegular Season - 15 | D |
| Dec 16 | Serie A | Torino 1–0EmpoliRegular Season - 16 | L |
| Dec 22 | Serie A | Empoli0–2 LazioRegular Season - 17 | L |
| Dec 30 | Serie A | Cagliari 0–0EmpoliRegular Season - 18 | D |
| January 2024Jan 07 | Serie A | Empoli0–3 AC MilanRegular Season - 19 | L |
| Jan 13 | Serie A | Hellas Verona2–1EmpoliRegular Season - 20 | L |
| Jan 21 | Serie A | Empoli3–0MonzaRegular Season - 21 | W |
| Jan 27 | Serie A | Juventus1–1EmpoliRegular Season - 22 | D |
| February 2024Feb 03 | Serie A | Empoli0–0GenoaRegular Season - 23 | D |
| Feb 09 | Serie A | Salernitana1–3EmpoliRegular Season - 24 | W |
| Feb 18 | Serie A | Empoli1–1FiorentinaRegular Season - 25 | D |
| Feb 24 | Serie A | Sassuolo2–3EmpoliRegular Season - 26 | W |
| March 2024Mar 03 | Serie A | Empoli0–1CagliariRegular Season - 27 | L |
| Mar 10 | Serie A | AC Milan1–0EmpoliRegular Season - 28 | L |
| Mar 15 | Serie A | Empoli0–1BolognaRegular Season - 29 | L |
| April 2024Apr 01 | Serie A | Inter2–0EmpoliRegular Season - 30 | L |
| Apr 06 | Serie A | Empoli3–2TorinoRegular Season - 31 | W |
| Apr 13 | Serie A | Lecce1–0EmpoliRegular Season - 32 | L |
| Apr 20 | Serie A | Empoli1–0NapoliRegular Season - 33 | W |
| Apr 28 | Serie A | Atalanta2–0EmpoliRegular Season - 34 | L |
| May 2024May 05 | Serie A | Empoli0–0FrosinoneRegular Season - 35 | D |
| May 12 | Serie A | Lazio2–0EmpoliRegular Season - 36 | L |
| May 19 | Serie A | Udinese1–1EmpoliRegular Season - 37 | D |
| May 26 | Serie A | Empoli2–1AS RomaRegular Season - 38 | W |
