| août 202418 août |  Serie A | Lazio 3–1 VeneziaRegular Season - 1 | V |
| 24 août | Serie A | Udinese 2–1LazioRegular Season - 2 | D |
| 31 août | Serie A | Lazio2–2 AC MilanRegular Season - 3 | N |
| septembre 202416 sept. | Serie A | Lazio2–1 Hellas VeronaRegular Season - 4 | V |
| 22 sept. | Serie A | Fiorentina 2–1LazioRegular Season - 5 | D |
| 25 sept. |  Europa League | Dynamo Kyiv 0–3LazioLeague Stage - 1 | V |
| 29 sept. | Serie A | Torino 2–3LazioRegular Season - 6 | V |
| octobre 202403 oct. | Europa League | Lazio4–1 NiceLeague Stage - 2 | V |
| 06 oct. | Serie A | Lazio2–1 EmpoliRegular Season - 7 | V |
| 19 oct. | Serie A | Juventus 1–0LazioRegular Season - 8 | D |
| 24 oct. | Europa League | Twente 0–2LazioLeague Stage - 3 | V |
| 27 oct. | Serie A | Lazio3–0 GenoaRegular Season - 9 | V |
| 31 oct. | Serie A | Como 1–5LazioRegular Season - 10 | V |
| novembre 202404 nov. | Serie A | Lazio2–1 CagliariRegular Season - 11 | V |
| 07 nov. | Europa League | Lazio2–1 FC PortoLeague Stage - 4 | V |
| 10 nov. | Serie A | Monza 0–1LazioRegular Season - 12 | V |
| 24 nov. | Serie A | Lazio3–0 BolognaRegular Season - 13 | V |
| 28 nov. | Europa League | Lazio0–0 LudogoretsLeague Stage - 5 | N |
| décembre 202401 déc. | Serie A | Parma 3–1LazioRegular Season - 14 | D |
| 08 déc. | Serie A | Napoli 0–1LazioRegular Season - 15 | V |
| 12 déc. | Europa League | Ajax 1–3LazioLeague Stage - 6 | V |
| 16 déc. | Serie A | Lazio0–6 InterRegular Season - 16 | D |
| 21 déc. | Serie A | Lecce 1–2LazioRegular Season - 17 | V |
| 28 déc. | Serie A | Lazio1–1 AtalantaRegular Season - 18 | N |
| janvier 202505 janv. | Serie A | AS Roma 2–0LazioRegular Season - 19 | D |
| 10 janv. | Serie A | Lazio1–1ComoRegular Season - 20 | N |
| 19 janv. | Serie A | Hellas Verona0–3LazioRegular Season - 21 | V |
| 23 janv. | Europa League | Lazio3–1 Real SociedadLeague Stage - 7 | V |
| 26 janv. | Serie A | Lazio1–2FiorentinaRegular Season - 22 | D |
| 30 janv. | Europa League | SC Braga 1–0LazioLeague Stage - 8 | D |
| février 202503 févr. | Serie A | Cagliari1–2LazioRegular Season - 23 | V |
| 09 févr. | Serie A | Lazio5–1MonzaRegular Season - 24 | V |
| 15 févr. | Serie A | Lazio2–2NapoliRegular Season - 25 | N |
| 22 févr. | Serie A | Venezia0–0LazioRegular Season - 26 | N |
| mars 202502 mars | Serie A | AC Milan1–2LazioRegular Season - 27 | V |
| 06 mars | Europa League | Plzen 1–2LazioRound of 16 | V |
| 10 mars | Serie A | Lazio1–1UdineseRegular Season - 28 | N |
| 13 mars | Europa League | Lazio1–1PlzenRound of 16 | N |
| 16 mars | Serie A | Bologna5–0LazioRegular Season - 29 | D |
| 31 mars | Serie A | Lazio1–1TorinoRegular Season - 30 | N |
| avril 202506 avr. | Serie A | Atalanta0–1LazioRegular Season - 31 | V |
| 10 avr. | Europa League | Bodo/Glimt 2–0LazioQuarter-finals | D |
| 13 avr. | Serie A | Lazio1–1AS RomaRegular Season - 32 | N |
| 17 avr. | Europa League | Lazio3–1Bodo/GlimtQuarter-finals | V |
| 23 avr. | Serie A | Genoa0–2LazioRegular Season - 33 | V |
| 28 avr. | Serie A | Lazio2–2ParmaRegular Season - 34 | N |
| mai 202504 mai | Serie A | Empoli0–1LazioRegular Season - 35 | V |
| 10 mai | Serie A | Lazio1–1JuventusRegular Season - 36 | N |
| 18 mai | Serie A | Inter2–2LazioRegular Season - 37 | N |
| 25 mai | Serie A | Lazio0–1LecceRegular Season - 38 | D |
