| août 202604 août |  Champions League | Sparta Praha 19:00 Lyon3rd Qualifying Round | — |
| 11 août | Champions League | Lyon19:00Sparta Praha3rd Qualifying Round | — |
| 22 août |  Ligue 1 | Toulouse 20:45LyonRegular Season - 1 | — |
| 29 août | Ligue 1 | Lyon20:45 Le HavreRegular Season - 2 | — |
| septembre 202605 sept. | Ligue 1 | Lyon17:00 AuxerreRegular Season - 3 | — |
| 12 sept. | Ligue 1 | Paris FC 17:00LyonRegular Season - 4 | — |
| 19 sept. | Ligue 1 | Lyon17:00 RennesRegular Season - 5 | — |
| octobre 202610 oct. | Ligue 1 | Lens 17:00LyonRegular Season - 6 | — |
| 17 oct. | Ligue 1 | Lyon17:00 NiceRegular Season - 7 | — |
| 25 oct. | Ligue 1 | Paris Saint Germain 20:45LyonRegular Season - 8 | — |
| 31 oct. | Ligue 1 | Lyon17:00 AngersRegular Season - 9 | — |
| novembre 202607 nov. | Ligue 1 | Stade Brestois 29 17:00LyonRegular Season - 10 | — |
| 21 nov. | Ligue 1 | Lille 17:00LyonRegular Season - 11 | — |
| 28 nov. | Ligue 1 | Lyon17:00 MonacoRegular Season - 12 | — |
| décembre 202605 déc. | Ligue 1 | Estac Troyes 17:00LyonRegular Season - 13 | — |
| 13 déc. | Ligue 1 | Lyon20:45 MarseilleRegular Season - 14 | — |
| janvier 202702 janv. | Ligue 1 | Le Mans 17:00LyonRegular Season - 15 | — |
| 16 janv. | Ligue 1 | Lyon17:00 LorientRegular Season - 16 | — |
| 23 janv. | Ligue 1 | Strasbourg 17:00LyonRegular Season - 17 | — |
| 30 janv. | Ligue 1 | Lyon17:00LilleRegular Season - 18 | — |
| février 202706 févr. | Ligue 1 | Rennes17:00LyonRegular Season - 19 | — |
| 13 févr. | Ligue 1 | Lyon17:00LensRegular Season - 20 | — |
| 20 févr. | Ligue 1 | Le Havre17:00LyonRegular Season - 21 | — |
| 27 févr. | Ligue 1 | Lyon17:00ToulouseRegular Season - 22 | — |
| mars 202706 mars | Ligue 1 | Monaco17:00LyonRegular Season - 23 | — |
| 13 mars | Ligue 1 | Lyon17:00Estac TroyesRegular Season - 24 | — |
| 21 mars | Ligue 1 | Marseille20:45LyonRegular Season - 25 | — |
| avril 202703 avr. | Ligue 1 | Nice17:00LyonRegular Season - 26 | — |
| 10 avr. | Ligue 1 | Lyon17:00StrasbourgRegular Season - 27 | — |
| 17 avr. | Ligue 1 | Angers17:00LyonRegular Season - 28 | — |
| 24 avr. | Ligue 1 | Lyon17:00Stade Brestois 29Regular Season - 29 | — |
| mai 202701 mai | Ligue 1 | Auxerre17:00LyonRegular Season - 30 | — |
| 09 mai | Ligue 1 | Lyon20:45Paris Saint GermainRegular Season - 31 | — |
| 16 mai | Ligue 1 | Lyon17:00Le MansRegular Season - 32 | — |
| 22 mai | Ligue 1 | Lorient17:00LyonRegular Season - 33 | — |
| 29 mai | Ligue 1 | Lyon21:00Paris FCRegular Season - 34 | — |
