| August 2022Aug 07 |  Ligue 1 | Angers 0–0 NantesRegular Season - 1 | D |
| Aug 14 | Ligue 1 | Auxerre 2–2AngersRegular Season - 2 | D |
| Aug 21 | Ligue 1 | Angers1–3 Stade Brestois 29Regular Season - 3 | L |
| Aug 28 | Ligue 1 | Estac Troyes 3–1AngersRegular Season - 4 | L |
| Aug 31 | Ligue 1 | Angers2–4 ReimsRegular Season - 5 | L |
| September 2022Sep 03 | Ligue 1 | Lyon 5–0AngersRegular Season - 6 | L |
| Sep 11 | Ligue 1 | Angers2–1 MontpellierRegular Season - 7 | W |
| Sep 18 | Ligue 1 | Nice 0–1AngersRegular Season - 8 | W |
| Sep 30 | Ligue 1 | Angers0–3 MarseilleRegular Season - 9 | L |
| October 2022Oct 09 | Ligue 1 | Angers2–3 StrasbourgRegular Season - 10 | L |
| Oct 16 | Ligue 1 | Toulouse 3–2AngersRegular Season - 11 | L |
| Oct 23 | Ligue 1 | Angers1–2 RennesRegular Season - 12 | L |
| Oct 30 | Ligue 1 | Monaco 2–0AngersRegular Season - 13 | L |
| November 2022Nov 05 | Ligue 1 | Angers1–2 LensRegular Season - 14 | L |
| Nov 13 | Ligue 1 | Lille 1–0AngersRegular Season - 15 | L |
| December 2022Dec 28 | Ligue 1 | Ajaccio 1–0AngersRegular Season - 16 | L |
| January 2023Jan 01 | Ligue 1 | Angers1–2 LorientRegular Season - 17 | L |
| Jan 06 |  Coupe de France | Strasbourg0–0AngersRound of 64 | D |
| Jan 11 | Ligue 1 | Paris Saint Germain 2–0AngersRegular Season - 18 | L |
| Jan 15 | Ligue 1 | Angers1–2 Clermont FootRegular Season - 19 | L |
| Jan 21 | Coupe de France | Strasbourg Koenigshoffen 0–1AngersRound of 32 | W |
| Jan 29 | Ligue 1 | Stade Brestois 294–0AngersRegular Season - 20 | L |
| February 2023Feb 01 | Ligue 1 | Angers1–2AjaccioRegular Season - 21 | L |
| Feb 05 | Ligue 1 | Lorient0–0AngersRegular Season - 22 | D |
| Feb 08 | Coupe de France | Angers1–1NantesRound of 16 | D |
| Feb 12 | Ligue 1 | Angers1–1AuxerreRegular Season - 23 | D |
| Feb 18 | Ligue 1 | Strasbourg2–1AngersRegular Season - 24 | L |
| Feb 25 | Ligue 1 | Angers1–3LyonRegular Season - 25 | L |
| March 2023Mar 05 | Ligue 1 | Montpellier5–0AngersRegular Season - 26 | L |
| Mar 12 | Ligue 1 | Angers0–2ToulouseRegular Season - 27 | L |
| Mar 18 | Ligue 1 | Lens3–0AngersRegular Season - 28 | L |
| April 2023Apr 02 | Ligue 1 | Angers1–1NiceRegular Season - 29 | D |
| Apr 08 | Ligue 1 | Angers1–0LilleRegular Season - 30 | W |
| Apr 16 | Ligue 1 | Clermont Foot2–1AngersRegular Season - 31 | L |
| Apr 21 | Ligue 1 | Angers1–2Paris Saint GermainRegular Season - 32 | L |
| Apr 30 | Ligue 1 | Rennes4–2AngersRegular Season - 33 | L |
| May 2023May 07 | Ligue 1 | Angers1–2MonacoRegular Season - 34 | L |
| May 14 | Ligue 1 | Marseille3–1AngersRegular Season - 35 | L |
| May 21 | Ligue 1 | Reims2–2AngersRegular Season - 36 | D |
| May 27 | Ligue 1 | Angers2–1Estac TroyesRegular Season - 37 | W |
| June 2023Jun 03 | Ligue 1 | Nantes1–0AngersRegular Season - 38 | L |
