| August 2024Aug 18 |  Ligue 1 | Rennes 3–0 LyonRegular Season - 1 | L |
| Aug 24 | Ligue 1 | Lyon0–2 MonacoRegular Season - 2 | L |
| Aug 30 | Ligue 1 | Lyon4–3 StrasbourgRegular Season - 3 | W |
| September 2024Sep 15 | Ligue 1 | Lens 0–0LyonRegular Season - 4 | D |
| Sep 22 | Ligue 1 | Lyon2–3 MarseilleRegular Season - 5 | L |
| Sep 26 |  Europa League | Lyon2–0 Olympiakos PiraeusLeague Stage - 1 | W |
| Sep 29 | Ligue 1 | Toulouse 1–2LyonRegular Season - 6 | W |
| October 2024Oct 03 | Europa League | Rangers 1–4LyonLeague Stage - 2 | W |
| Oct 06 | Ligue 1 | Lyon2–0 NantesRegular Season - 7 | W |
| Oct 20 | Ligue 1 | Le Havre 0–4LyonRegular Season - 8 | W |
| Oct 24 | Europa League | Lyon0–1 BeşiktaşLeague Stage - 3 | L |
| Oct 27 | Ligue 1 | Lyon2–2 AuxerreRegular Season - 9 | D |
| November 2024Nov 01 | Ligue 1 | Lille 1–1LyonRegular Season - 10 | D |
| Nov 07 | Europa League | 1899 Hoffenheim 2–2LyonLeague Stage - 4 | D |
| Nov 10 | Ligue 1 | Lyon1–0 Saint EtienneRegular Season - 11 | W |
| Nov 23 | Ligue 1 | Reims 1–1LyonRegular Season - 12 | D |
| Nov 28 | Europa League | Qarabag 1–4LyonLeague Stage - 5 | W |
| December 2024Dec 01 | Ligue 1 | Lyon4–1 NiceRegular Season - 13 | W |
| Dec 07 | Ligue 1 | Angers 0–3LyonRegular Season - 14 | W |
| Dec 12 | Europa League | Lyon3–2 Eintracht FrankfurtLeague Stage - 6 | W |
| Dec 15 | Ligue 1 | Paris Saint Germain 3–1LyonRegular Season - 15 | L |
| January 2025Jan 04 | Ligue 1 | Lyon1–0 MontpellierRegular Season - 16 | W |
| Jan 11 | Ligue 1 | Stade Brestois 29 2–1LyonRegular Season - 17 | L |
| Jan 18 | Ligue 1 | Lyon0–0ToulouseRegular Season - 18 | D |
| Jan 23 | Europa League | Fenerbahçe 0–0LyonLeague Stage - 7 | D |
| Jan 26 | Ligue 1 | Nantes1–1LyonRegular Season - 19 | D |
| Jan 30 | Europa League | Lyon1–1 LudogoretsLeague Stage - 8 | D |
| February 2025Feb 02 | Ligue 1 | Marseille3–2LyonRegular Season - 20 | L |
| Feb 09 | Ligue 1 | Lyon4–0ReimsRegular Season - 21 | W |
| Feb 16 | Ligue 1 | Montpellier1–4LyonRegular Season - 22 | W |
| Feb 23 | Ligue 1 | Lyon2–3Paris Saint GermainRegular Season - 23 | L |
| March 2025Mar 02 | Ligue 1 | Lyon2–1Stade Brestois 29Regular Season - 24 | W |
| Mar 06 | Europa League | FCSB 1–3LyonRound of 16 | W |
| Mar 09 | Ligue 1 | Nice0–2LyonRegular Season - 25 | W |
| Mar 13 | Europa League | Lyon4–0FCSBRound of 16 | W |
| Mar 16 | Ligue 1 | Lyon4–2Le HavreRegular Season - 26 | W |
| Mar 28 | Ligue 1 | Strasbourg4–2LyonRegular Season - 27 | L |
| April 2025Apr 05 | Ligue 1 | Lyon2–1LilleRegular Season - 28 | W |
| Apr 10 | Europa League | Lyon2–2 Manchester UnitedQuarter-finals | D |
| Apr 13 | Ligue 1 | Auxerre1–3LyonRegular Season - 29 | W |
| Apr 17 | Europa League | Manchester United5–4LyonQuarter-finals | L |
| Apr 20 | Ligue 1 | Saint Etienne2–1LyonRegular Season - 30 | L |
| Apr 26 | Ligue 1 | Lyon4–1RennesRegular Season - 31 | W |
| May 2025May 04 | Ligue 1 | Lyon1–2LensRegular Season - 32 | L |
| May 10 | Ligue 1 | Monaco2–0LyonRegular Season - 33 | L |
| May 17 | Ligue 1 | Lyon2–0AngersRegular Season - 34 | W |
