| August 2017Aug 26 |  Liga Profesional Argentina | Talleres Cordoba 5–2 LanusRegular Season - 1 | L |
| September 2017Sep 11 | Liga Profesional Argentina | Lanus0–1 Boca JuniorsRegular Season - 2 | L |
| Sep 17 | Liga Profesional Argentina | Independiente 0–1LanusRegular Season - 3 | W |
| Sep 26 | Liga Profesional Argentina | Lanus1–0 Newells Old BoysRegular Season - 4 | W |
| Sep 30 | Liga Profesional Argentina | Gimnasia L.P. 1–3LanusRegular Season - 5 | W |
| October 2017Oct 14 | Liga Profesional Argentina | Lanus2–1 Union Santa FeRegular Season - 6 | W |
| Oct 28 | Liga Profesional Argentina | Huracan 4–0LanusRegular Season - 7 | L |
| November 2017Nov 04 | Liga Profesional Argentina | Lanus0–2 Olimpo Bahia BlancaRegular Season - 8 | L |
| Nov 18 | Liga Profesional Argentina | Defensa Y Justicia 3–0LanusRegular Season - 9 | L |
| December 2017Dec 04 | Liga Profesional Argentina | Lanus0–0 Velez SarsfieldRegular Season - 11 | D |
| Dec 12 | Liga Profesional Argentina | Chacarita Juniors 3–0LanusRegular Season - 12 | L |
| January 2018Jan 27 | Liga Profesional Argentina | Lanus1–1 PatronatoRegular Season - 13 | D |
| February 2018Feb 03 | Liga Profesional Argentina | Belgrano Cordoba 0–0LanusRegular Season - 14 | D |
| Feb 08 | Liga Profesional Argentina | Godoy Cruz 4–1LanusRegular Season - 10 | L |
| Feb 12 | Liga Profesional Argentina | Lanus1–0 River PlateRegular Season - 15 | W |
| Feb 16 | Liga Profesional Argentina | Racing Club 3–1LanusRegular Season - 16 | L |
| Feb 24 | Liga Profesional Argentina | Lanus1–1 Rosario CentralRegular Season - 17 | D |
| March 2018Mar 02 | Liga Profesional Argentina | Arsenal Sarandi 2–1LanusRegular Season - 18 | L |
| Mar 11 | Liga Profesional Argentina | Lanus0–0 Estudiantes L.P.Regular Season - 19 | D |
| Mar 17 | Liga Profesional Argentina | Colon Santa Fe 1–2LanusRegular Season - 20 | W |
| April 2018Apr 02 | Liga Profesional Argentina | Lanus0–2 San LorenzoRegular Season - 21 | L |
| Apr 07 | Liga Profesional Argentina | Temperley 2–2LanusRegular Season - 22 | D |
| Apr 14 | Liga Profesional Argentina | Lanus0–0 BanfieldRegular Season - 23 | D |
| Apr 21 | Liga Profesional Argentina | San Martin S.J. 1–1LanusRegular Season - 24 | D |
| Apr 28 | Liga Profesional Argentina | Lanus0–0 Argentinos JRSRegular Season - 25 | D |
| May 2018May 06 | Liga Profesional Argentina | Tigre 0–0LanusRegular Season - 26 | D |
| May 12 | Liga Profesional Argentina | Lanus0–0 Atletico TucumanRegular Season - 27 | D |
