| August 2018Aug 11 |  Ligue 1 | Lille 3–1 RennesRegular Season - 1 | L |
| Aug 18 | Ligue 1 | Rennes1–0 AngersRegular Season - 2 | W |
| Aug 26 | Ligue 1 | Marseille 2–2RennesRegular Season - 3 | D |
| September 2018Sep 02 | Ligue 1 | Rennes2–0 BordeauxRegular Season - 4 | W |
| Sep 14 | Ligue 1 | Nice 2–1RennesRegular Season - 5 | L |
| Sep 20 |  Europa League | Rennes2–1 FK JablonecGroup Stage - 1 | W |
| Sep 23 | Ligue 1 | Rennes1–3 Paris Saint GermainRegular Season - 6 | L |
| Sep 26 | Ligue 1 | Amiens 2–1RennesRegular Season - 7 | L |
| Sep 30 | Ligue 1 | Rennes1–1 ToulouseRegular Season - 8 | D |
| October 2018Oct 04 | Europa League | FC Astana 2–0RennesGroup Stage - 2 | L |
| Oct 07 | Ligue 1 | Monaco 1–2RennesRegular Season - 9 | W |
| Oct 21 | Ligue 1 | Saint Etienne 1–1RennesRegular Season - 10 | D |
| Oct 25 | Europa League | Rennes1–2 Dynamo KyivGroup Stage - 3 | L |
| Oct 28 | Ligue 1 | Rennes0–2 ReimsRegular Season - 11 | L |
| November 2018Nov 03 | Ligue 1 | Caen 1–2RennesRegular Season - 12 | W |
| Nov 08 | Europa League | Dynamo Kyiv3–1RennesGroup Stage - 4 | L |
| Nov 11 | Ligue 1 | Rennes1–1 NantesRegular Season - 13 | D |
| Nov 25 | Ligue 1 | Montpellier 2–2RennesRegular Season - 14 | D |
| Nov 29 | Europa League | FK Jablonec0–1RennesGroup Stage - 5 | W |
| December 2018Dec 02 | Ligue 1 | Rennes1–4 StrasbourgRegular Season - 15 | L |
| Dec 05 | Ligue 1 | Lyon 0–2RennesRegular Season - 16 | W |
| Dec 08 | Ligue 1 | Rennes2–0 DijonRegular Season - 17 | W |
| Dec 13 | Europa League | Rennes2–0FC AstanaGroup Stage - 6 | W |
| Dec 22 | Ligue 1 | Rennes4–0 NimesRegular Season - 19 | W |
| January 2019Jan 13 | Ligue 1 | Nantes0–1RennesRegular Season - 20 | W |
| Jan 16 | Ligue 1 | Guingamp 2–1RennesRegular Season - 18 | L |
| Jan 20 | Ligue 1 | Rennes0–0MontpellierRegular Season - 21 | D |
| Jan 27 | Ligue 1 | Paris Saint Germain4–1RennesRegular Season - 22 | L |
| February 2019Feb 02 | Ligue 1 | Rennes1–0AmiensRegular Season - 23 | W |
| Feb 10 | Ligue 1 | Rennes3–0Saint EtienneRegular Season - 24 | W |
| Feb 14 | Europa League | Rennes3–3 Real Betis16th Finals | D |
| Feb 17 | Ligue 1 | Reims2–0RennesRegular Season - 25 | L |
| Feb 21 | Europa League | Real Betis1–3Rennes16th Finals | W |
| Feb 24 | Ligue 1 | Rennes1–1MarseilleRegular Season - 26 | D |
| March 2019Mar 07 | Europa League | Rennes3–1 Arsenal8th Finals | W |
| Mar 10 | Ligue 1 | Rennes3–1CaenRegular Season - 28 | W |
| Mar 14 | Europa League | Arsenal3–0Rennes8th Finals | L |
| Mar 17 | Ligue 1 | Bordeaux1–1RennesRegular Season - 29 | D |
| Mar 29 | Ligue 1 | Rennes0–1LyonRegular Season - 30 | L |
| April 2019Apr 06 | Ligue 1 | Angers3–3RennesRegular Season - 31 | D |
| Apr 09 | Ligue 1 | Nimes3–1RennesRegular Season - 27 | L |
| Apr 14 | Ligue 1 | Rennes0–0NiceRegular Season - 32 | D |
| Apr 19 | Ligue 1 | Dijon3–2RennesRegular Season - 33 | L |
| May 2019May 01 | Ligue 1 | Rennes2–2MonacoRegular Season - 34 | D |
| May 05 | Ligue 1 | Toulouse2–2RennesRegular Season - 35 | D |
| May 12 | Ligue 1 | Rennes1–1GuingampRegular Season - 36 | D |
| May 18 | Ligue 1 | Strasbourg0–2RennesRegular Season - 37 | W |
| May 24 | Ligue 1 | Rennes3–1LilleRegular Season - 38 | W |
